A simple blood test to detect neurodegenerative diseases


C. Garrido



A simple blood test may be enough to accurately determine if behind the cognitive problems that a person is suffering there is a neurodegenerative disease overwhelming. It is the conclusion of a study, published in Nature Communications, which has discovered how the levels of a protein called neurofilament light chain (NfL) in the blood can identify those patients who could have neurodegenerative pathologies such as Down syndrome dementia, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, when the clinical symptoms are not definitive.

‘For the first time in a series of disorders we have shown that a single biomarker can indicate the presence of underlying neurodegeneration with excellent precision. Even if is not specific to any disorder in

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